Which is the worst time of the year for people with ITP?

 

Photo by Mike Newbry on Unsplash

 

Immune thrombocytopenia (ITP) is an autoimmune disease. This means the immune system mistakenly attacks and destroys platelets, the blood cells that help stop bleeding.

In children, ITP is more often diagnosed during the fall and winter. This pattern suggests that infections or environmental factors, such as viruses or some vaccines, may trigger the immune system to attack platelets.

Researchers wondered if the time of year also affected when adults develop ITP. They studied 165 adults with primary ITP. Most people were diagnosed in the spring, especially in May. Fewer people were diagnosed during the summer, fall, and winter.

Almost everyone was first treated with corticosteroids. About 1 in 3 people did not respond well to this treatment. These patients were also more likely to be diagnosed in the spring. More than half of the people in the study developed chronic (long-lasting) ITP. Many of these cases were also first diagnosed in the spring.

This was the first study to find a possible link between the seasons and ITP in adults. The researchers think that high pollen levels in the spring, especially in places with a Mediterranean climate, may play a role. More research is needed to find out if pollen or other seasonal factors affect when ITP develops.


Source: Tombak A et al.  “Seasonal Association of Immune Thrombocytopenia in Adults” Balkan Med J 2015;32:347-5


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