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Living with Zika virus infectious disease

An infection spread mainly by mosquito bites that usually causes mild illness, with fever, rash, joint pain and red eyes.

Understanding Zika virus infectious disease

Zika virus infection is an illness spread mainly by the bite of an infected mosquito, and it is usually mild.

Symptoms usually last from several days to a week. The virus can also pass from a pregnant mother to her child, through sex, and, in some reported cases, through blood transfusion. GARD says the full range of health problems from infection during pregnancy is still being studied. No vaccine exists.

Signs & symptoms

Symptoms vary from person to person. GARD lists these among the most common:

  • Fever
  • Skin rash and itching
  • Joint pain
  • Muscle aches
  • Headache
  • Red eyes (conjunctivitis)

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Your doctor may refer you to a specialist who knows rare conditions.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

Care & treatment

Care team
A doctor familiar with rare conditions, plus specialists as needed
Expert care
Ask about multidisciplinary care centers for rare conditions
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with rare disease patient organizations for support
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
Should I be tested for Zika after travel to an affected area?
What should I know if I am pregnant or planning a pregnancy?
How can I prevent mosquito bites and spread to partners?

Quick facts

Symptoms usually startany time in life

Zika virus causes this infection. It spreads mainly through mosquito bites, from mother to child in pregnancy, and through sexual contact.

Infectious

Also known as: zika; zika fever; zika virus caused disease or disorder; zika virus disease; zika virus disease or disorder; zika virus infection

Patient organizations

Rare-disease groups that can help

Source: NIH GARD · Zika virus infectious diseaseGARD ID 12894 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Zika virus infectious disease.

Explore the Zika virus infectious disease blog

Explore research for Zika virus infectious disease

Explore actively recruiting Zika virus infectious disease studies with HealthSpark.

HealthSpark

Find actively recruiting studies for Zika virus infectious disease with HealthSpark. Share your city to explore research near you.

  • Recruiting studies from ClinicalTrials.gov
  • Share your city to look for research near you
  • Eligibility is confirmed by the study team

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I can help you find recruiting Zika virus infectious disease studies. Enter a ZIP code, address or city below and I'll look within 50 miles.

Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.

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