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Living with Urethra cancer

A rare cancer of the tube that carries urine out of the body, found more often in men than in women.

Understanding Urethra cancer

Urethra cancer is a rare cancer that starts in the urethra, the tube that carries urine from the bladder to outside the body.

It occurs more often in men than in women. Types are named for the cells that become cancer: squamous cell carcinoma (the most common), transitional cell carcinoma, and adenocarcinoma. GARD says it can spread quickly to nearby tissues and is often found in nearby lymph nodes by the time it is diagnosed.

Signs & symptoms

GARD doesn't list specific symptoms for this condition yet.

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Your doctor may refer you to a specialist who knows rare conditions.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

Care & treatment

Care team
A doctor familiar with rare conditions, plus specialists as needed
Expert care
Ask about multidisciplinary care centers for rare conditions
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with American Cancer Society
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
Which type of urethral cancer do I have?
Has the cancer spread to nearby lymph nodes?
Which specialists will be on my care team?

Quick facts

GARD doesn't describe a cause for this condition yet. It explains that the cancer types are named for the kind of cell that becomes cancerous.

Also known as: cancer of urethra; malignant neoplasm of the urethra; malignant neoplasm of urethra; malignant tumor of the urethra; malignant tumor of urethra; malignant tumour of the urethra

Patient organizations

Source: NIH GARD · Urethra cancerGARD ID 9390 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Urethra cancer.

Explore the Urethra cancer blog

Explore research for Urethra cancer

Explore actively recruiting Urethra cancer studies with HealthSpark.

HealthSpark

Find actively recruiting studies for Urethra cancer with HealthSpark. Share your city to explore research near you.

  • Recruiting studies from ClinicalTrials.gov
  • Share your city to look for research near you
  • Eligibility is confirmed by the study team

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I can help you find recruiting Urethra cancer studies. Enter a ZIP code, address or city below and I'll look within 50 miles.

Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.

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