Living with Solitary median maxillary central incisor syndrome
A rare condition in which a child has only one upper front tooth, sometimes with other differences of the head and face.
Understanding Solitary median maxillary central incisor syndrome
It affects both the baby tooth and the permanent tooth. Other features can include eyes set close together, a small head, short stature, a blocked back nasal passage and learning disability. Some people have a more serious brain difference called holoprosencephaly.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Only one upper front tooth
- Eyes set close together
- Small head (microcephaly)
- Short stature
- Blocked back of the nasal passage
- Learning disability
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Your doctor may refer you to a specialist who knows rare conditions.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
Care & treatment
- Care team
- A doctor familiar with rare conditions, plus specialists as needed
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Families for HoPE
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD doesn't list a gene. It is inherited in an autosomal dominant pattern, meaning one changed copy of a gene is enough.
Also known as: fused incisors; only one upper front tooth; single central incisor; single central incisor syndrome; single central maxillary incisor; single central upper incisor
Patient organizations
- Families for HoPESolitary median maxillary central incisor syndrome · United States
You are more than your diagnosis
Perspectives from people navigating life with Solitary median maxillary central incisor syndrome.
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