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Living with Relapsing fever

A bacterial infection with repeated bouts of fever, caused by Borrelia bacteria other than those that cause Lyme disease.

Understanding Relapsing fever

Relapsing fever is an infection caused by bacteria of the genus Borrelia, not including the ones that cause Lyme disease.

It can occur at any time in life. GARD lists fever, headache, and muscle aches among the common features.

Signs & symptoms

Symptoms vary from person to person. GARD lists these among the most common:

  • Fever
  • Headache
  • Muscle aches
  • Yellowing of the skin and eyes (jaundice)
  • Anemia (low red blood cells)
  • Low platelet count

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Your doctor may refer you to a specialist who knows rare conditions.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

Care & treatment

Care team
A doctor familiar with rare conditions, plus specialists as needed
Expert care
Ask about multidisciplinary care centers for rare conditions
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with rare disease patient organizations for support
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
How is relapsing fever diagnosed and treated?
Why does the fever keep coming back?
What can I do to avoid being exposed again?

Quick facts

Symptoms usually startany time in life

It is caused by Borrelia bacteria, other than the Borrelia burgdorferi complex that causes Lyme disease.

Infectious

Patient organizations

Rare-disease groups that can help

Source: NIH GARD · Relapsing feverGARD ID 19171 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Relapsing fever.

Explore the Relapsing fever blog

Explore research for Relapsing fever

Explore actively recruiting Relapsing fever studies with HealthSpark.

HealthSpark

Find actively recruiting studies for Relapsing fever with HealthSpark. Share your city to explore research near you.

  • Recruiting studies from ClinicalTrials.gov
  • Share your city to look for research near you
  • Eligibility is confirmed by the study team

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I can help you find recruiting Relapsing fever studies. Enter a ZIP code, address or city below and I'll look within 50 miles.

Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.

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