Living with Pseudohypoaldosteronism, type 2
A condition that causes high potassium and high blood pressure even though the kidneys work normally.
Understanding Pseudohypoaldosteronism, type 2
People have high blood pressure and high blood potassium (hyperkalemia) despite normal kidney function. Age at onset varies, from infancy to adulthood. High potassium usually comes first, and high blood pressure develops later. Blood also tends to have extra chloride and acid. Some people have high calcium in the urine.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- High blood pressure (hypertension)
- Nausea and vomiting
- Extreme tiredness
- Muscle weakness
- High potassium in the blood (hyperkalemia)
- Slow growth
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include genetic specialists and kidney specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
Care & treatment
- Care team
- Genetic specialists (geneticists); Kidney specialists (nephrologists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with National Kidney Foundation and other patient organizations
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD lists both autosomal dominant and autosomal recessive inheritance. It doesn't name a gene here.
Also known as: chloride shunt syndrome; familial hyperkalemic hypertension; gordon hyperkalemia-hypertension syndrome; hyperkalemia-hypertension syndrome, gordon type; hypertensive hyperkalemia; mineralocorticoid resistant hyperkalemia
Patient organizations
- National Kidney FoundationKidney diseases · United States
- Renal Support NetworkKidney diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Pseudohypoaldosteronism, type 2.
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