Living with Palmoplantar pustulosis
A skin condition with painful, pus-filled blisters on the palms and soles that come and go.
Understanding Palmoplantar pustulosis
The blisters are sterile, which means they are not caused by an infection. They appear on red, peeling skin and may also affect the sides of the hands and feet. The nails can also be affected. The condition is chronic and tends to flare up and calm down. GARD lists links to psoriatic arthritis, thyroid problems, and smoking.
Signs & symptoms
GARD doesn't list specific symptoms in its symptom list, but the summary describes:
- Painful pustules on palms and soles
- Red, peeling skin
- Pitted or thickened nails
- Nails lifting off the nail bed
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include genetic specialists and skin, hair, and nail specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
- 4Connect with expert centers
Global Autoimmune Institute and National Psoriasis Foundation may keep lists of experts for this condition.
Care & treatment
- Care team
- Genetic specialists (geneticists); Skin, hair, and nail specialists (dermatologists)
- Expert care
- Expert lists: Global Autoimmune Institute, National Psoriasis Foundation
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Global Autoimmune Institute and other patient organizations
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD lists changes in genes (also called variants) in both autosomal dominant and autosomal recessive patterns, but doesn't name a specific gene.
Also known as: acropustulosis; localised pustular psoriasis; localized pustular psoriasis; lpp; palmoplantar pustular psoriasis; palmoplantar pustules
Patient organizations
- Global Autoimmune InstitutePalmoplantar pustulosis · United States
- National Psoriasis FoundationPalmoplantar pustulosis · United States
- Children's Skin Disease FoundationSkin diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Palmoplantar pustulosis.
Explore research for Palmoplantar pustulosis
Explore actively recruiting Palmoplantar pustulosis studies with HealthSpark.
Find actively recruiting studies for Palmoplantar pustulosis with HealthSpark. Share your city to explore research near you.
- Recruiting studies from ClinicalTrials.gov
- Share your city to look for research near you
- Eligibility is confirmed by the study team
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Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.
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