Living with Oligodontia-cancer predisposition syndrome
A rare genetic condition with six or more permanent teeth missing from birth and a higher chance of certain cancers.
Understanding Oligodontia-cancer predisposition syndrome
The teeth never develop, which can cause gaps in the smile and problems with chewing and jaw alignment. There is a higher chance of cancers, especially in the digestive tract, such as intestinal polyps or colorectal cancer at a young age, and of breast cancer. Some people also have signs of ectodermal dysplasia, such as sparse scalp hair and thin or missing eyebrows.
Signs & symptoms
GARD doesn't list specific symptoms for this condition yet. Based on its summary, features may include:
- Six or more permanent teeth missing from birth
- Problems with chewing and jaw alignment
- Higher chance of digestive tract cancers and polyps
- Higher chance of breast cancer
- Sparse scalp hair
- Thin or missing eyebrows
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Your doctor may refer you to a specialist who knows rare conditions.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
- 4Connect with expert centers
FORCE: Facing Our Risk of Cancer Empowered may keep lists of experts for this condition.
Care & treatment
- Care team
- A doctor familiar with rare conditions, plus specialists as needed
- Expert care
- Expert lists: FORCE: Facing Our Risk of Cancer Empowered
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with FORCE: Facing Our Risk of Cancer Empowered
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD calls this a rare genetic condition. It doesn't list a specific gene or how it is inherited.
Also known as: autosomal dominant ectodermal dysplasia-cancer predisposition syndrome; odcrcs; oligodontia-colorectal cancer syndrome; tooth agenesis-colorectal cancer syndrome
Patient organizations
- FORCE: Facing Our Risk of Cancer EmpoweredOligodontia-cancer predisposition syndrome · United States
You are more than your diagnosis
Perspectives from people navigating life with Oligodontia-cancer predisposition syndrome.
Explore research for Oligodontia-cancer predisposition syndrome
Explore actively recruiting Oligodontia-cancer predisposition syndrome studies with HealthSpark.
Find actively recruiting studies for Oligodontia-cancer predisposition syndrome with HealthSpark. Share your city to explore research near you.
- Recruiting studies from ClinicalTrials.gov
- Share your city to look for research near you
- Eligibility is confirmed by the study team
Powered by HealthSpark, our AI chat helper
I can help you find recruiting Oligodontia-cancer predisposition syndrome studies. Enter a ZIP code, address or city below and I'll look within 50 miles.
Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.
Get Signals for Oligodontia-cancer predisposition syndrome
Stay in the loop with community stories and updates from medical researchers.
Create a living journal that talks back
HealthStory evolves private journaling with a living AI journal that talks back and asks thoughtful questions, helping you capture your Oligodontia-cancer predisposition syndrome experiences more deeply and prepare for better conversations with your doctors and care team.
Your journal is private. Sharing your story publicly is a separate choice, made with Share your story above.