Living with Nephrogenic syndrome of inappropriate antidiuresis
A condition in which the body holds on to too much water and blood sodium gets low; it is more common in older people.
Understanding Nephrogenic syndrome of inappropriate antidiuresis
Too much antidiuretic hormone causes the body to hold on to water and sodium levels to fall. It is most common among older people. Pain, stress, exercise, low blood sugar, some heart, thyroid, kidney, or adrenal conditions, and some medicines can cause it. Lung disorders and certain cancers may raise the risk. GARD lists onset in childhood for the inherited form.
Signs & symptoms
GARD lists these among the most common:
- Irritability
- Seizures
- Higher systolic blood pressure
- Low renin levels in the blood
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include genetic specialists and kidney specialists.
- 3Consider genetic testing
Changes in AVPR2 are linked to this condition. Genetic testing and counseling can help confirm a diagnosis and explain what it means for your family.
Care & treatment
- Care team
- Genetic specialists (geneticists); Kidney specialists (nephrologists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with National Kidney Foundation and other patient organizations
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
It has many causes, including pain, stress, low blood sugar, certain conditions, and some medicines. GARD also lists changes in the AVPR2 gene, with X-linked inheritance.
Also known as: nephrogenic syndrome of inappropriate antidiuresis, x-linked recessive; nsiad; nsiad - nephrogenic syndrome of inappropriate antidiuresis
Patient organizations
- National Kidney FoundationKidney diseases · United States
- Renal Support NetworkKidney diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Nephrogenic syndrome of inappropriate antidiuresis.
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