Skip to content
knowrare
HealthSignal
Your condition community

Living with Melioidosis

An infection caused by bacteria in soil and water, common in tropical areas, with symptoms that can look like pneumonia or tuberculosis.

Understanding Melioidosis

Melioidosis is an infectious disease caused by the bacteria Burkholderia pseudomallei, which live in soil and water.

It is rare in the United States but common in tropical or subtropical places such as Southeast Asia, Africa, and Australia. Symptoms vary a lot and can look like tuberculosis or pneumonia. Healthy people can get sick, but people with diabetes, liver, kidney, or lung disease, thalassemia, cancer, or some autoimmune diseases may be more severely affected.

Signs & symptoms

Symptoms vary from person to person. GARD lists these among the most common:

  • Fever
  • Cough and trouble breathing
  • Pneumonia and lung infection
  • Lung abscess
  • Pain or swelling
  • Headache

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Your doctor may refer you to a specialist who knows rare conditions.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

Care & treatment

Care team
A doctor familiar with rare conditions, plus specialists as needed
Expert care
Ask about multidisciplinary care centers for rare conditions
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with rare disease patient organizations for support
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
What tests confirm melioidosis?
Does my other health condition raise my risk of a more serious illness?
Which specialists, such as infectious disease doctors, should I see?

Quick facts

Symptoms usually startany time in life

It is caused by Burkholderia pseudomallei bacteria that are commonly found in soil and water. GARD lists no gene or inheritance pattern.

Infectious

Also known as: acute and fulminating melioidosis; burkholderia pseudomallei caused disease or disorder; burkholderia pseudomallei disease or disorder; burkholderia pseudomallei infectious disease; infection due to burkholderia pseudomallei; infection due to malleomyces pseudomallei

Patient organizations

Rare-disease groups that can help

Source: NIH GARD · MelioidosisGARD ID 9546 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Melioidosis.

Explore the Melioidosis blog

Explore research for Melioidosis

Explore actively recruiting Melioidosis studies with HealthSpark.

HealthSpark

Find actively recruiting studies for Melioidosis with HealthSpark. Share your city to explore research near you.

  • Recruiting studies from ClinicalTrials.gov
  • Share your city to look for research near you
  • Eligibility is confirmed by the study team

Powered by HealthSpark, our AI chat helper

I can help you find recruiting Melioidosis studies. Enter a ZIP code, address or city below and I'll look within 50 miles.

Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.

Get Signals for Melioidosis

Stay in the loop with community stories and updates from medical researchers.

HealthStoryfor Melioidosis

Create a living journal that talks back

HealthStory evolves private journaling with a living AI journal that talks back and asks thoughtful questions, helping you capture your Melioidosis experiences more deeply and prepare for better conversations with your doctors and care team.

Start your Melioidosis journal

Your journal is private. Sharing your story publicly is a separate choice, made with Share your story above.