Living with Malignant lymphoma, large B-cell, diffuse
A fast-growing cancer of immune cells called B cells, usually found in adults, often starting with swollen lymph nodes.
Understanding Malignant lymphoma, large B-cell, diffuse
B lymphocytes grow and multiply without control. DLBCL happens mostly in adults. It can start in the lymph nodes or outside the lymphatic system, such as in the gut, testes, thyroid, skin, breast, bone, or brain. The first sign is often painless, rapid swelling from enlarged lymph nodes.
Signs & symptoms
GARD doesn't list a separate symptom list, but its summary describes these:
- Swelling in the neck, armpit, abdomen, or groin
- Swelling that is usually painless but may be painful
- Night sweats
- Unexplained fevers
- Weight loss
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include blood and bone marrow specialists and cancer specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
Care & treatment
- Care team
- Blood and bone marrow specialists (hematologists); Cancer specialists (oncologists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with HealthTree Foundation and other patient organizations
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD says lymphomas occur when B lymphocytes grow and multiply uncontrollably. GARD doesn't name a gene or other cause.
Also known as: centroblastic diffuse large b-cell malignant lymphoma; centroblastic diffuse malignant lymphoma; centroblastic malignant lymphoma; diffuse large b cell lymphoma; diffuse large b cell malignant lymphoma; diffuse large b-cell lymphoma
Patient organizations
- HealthTree FoundationMalignant lymphoma, large B-cell, diffuse · United States
- Lymphoma Research FoundationMalignant lymphoma, large B-cell, diffuse · United States
You are more than your diagnosis
Perspectives from people navigating life with Malignant lymphoma, large B-cell, diffuse.
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