Living with Magic syndrome
A rare condition of the immune system with cartilage inflammation and mouth and genital sores.
Understanding Magic syndrome
It causes inflammation of cartilage in the ears, nose, throat, and rib cage. It can also cause repeated ulcers in the mouth and genitals. Some people have eye problems, joint pain, fever, colitis, or swollen veins with clots. Symptoms of polychondritis usually come after those of Behçet's disease. It can start from childhood to adulthood.
Signs & symptoms
GARD doesn't list a separate symptom list, but its summary describes these symptoms:
- Inflamed cartilage in the ears, nose, throat, and ribs
- Repeated mouth and genital ulcers
- Eye problems
- Joint pain
- Fever
- Colitis (inflamed lining of the colon)
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include autoimmune and inflammatory disease specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
Care & treatment
- Care team
- autoimmune and inflammatory disease specialists (rheumatologists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with The International Foundation for Autoimmune & Autoinflammatory Arthritis
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD doesn't describe a cause for this condition yet.
Also known as: magic (mouth and genital ulcers inflamed cartilage) syndrome; mouth and genital ulcers with inflamed cartilage; mouth and genital ulcers with inflamed cartilage syndrome; mouth and genital ulcers-inflamed cartilage syndrome
Patient organizations
- The International Foundation for Autoimmune & Autoinflammatory ArthritisMagic syndrome · United States
You are more than your diagnosis
Perspectives from people navigating life with Magic syndrome.
Explore research for Magic syndrome
Explore actively recruiting Magic syndrome studies with HealthSpark.
Find actively recruiting studies for Magic syndrome with HealthSpark. Share your city to explore research near you.
- Recruiting studies from ClinicalTrials.gov
- Share your city to look for research near you
- Eligibility is confirmed by the study team
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Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.
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