Living with Keratosis palmoplantaris striata 3
A genetic skin condition with patches of thick, scaly skin on the palms and soles, caused by a change in the KRT1 gene.
Understanding Keratosis palmoplantaris striata 3
The thick skin affects the palms of the hands and the soles of the feet. GARD does not list the age when it starts.
Signs & symptoms
GARD lists this among the most common symptoms:
- Thick, scaly skin on the palms and soles
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Your doctor may refer you to a specialist who knows rare conditions.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
- 4Connect with expert centers
Foundation for Ichthyosis and Related Skin Types may keep lists of experts for this condition.
Care & treatment
- Care team
- A doctor familiar with rare conditions, plus specialists as needed
- Expert care
- Expert lists: Foundation for Ichthyosis and Related Skin Types
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Foundation for Ichthyosis and Related Skin Types
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
A change in the keratin-1 (KRT1) gene causes this condition. It is autosomal dominant, meaning one changed copy of the gene is enough.
Also known as: keratoderma, palmoplantar, striate form iii; keratosis palmoplantaris striata iii; keratosis palmoplantaris striata type 3; krt1 striate palmoplantar keratoderma; ppks3; striate palmoplantar keratoderma caused by mutation in krt1
Patient organizations
- Foundation for Ichthyosis and Related Skin TypesKeratosis palmoplantaris striata 3 · United States
You are more than your diagnosis
Perspectives from people navigating life with Keratosis palmoplantaris striata 3.
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