Living with Keratosis palmaris et plantaris-clinodactyly syndrome
A rare inherited condition with thick skin on the palms and soles and a curved little finger, present from birth.
Understanding Keratosis palmaris et plantaris-clinodactyly syndrome
It is noticed in newborns. The skin on the palms and soles is thickened, and the little finger curves (clinodactyly). People may also sweat more than usual.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Thickened skin on the palms and soles
- Curved little finger (clinodactyly)
- Excessive sweating
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include genetic specialists and skin, hair, and nail specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
- 4Connect with expert centers
Foundation for Ichthyosis and Related Skin Types may keep lists of experts for this condition.
Care & treatment
- Care team
- Genetic specialists (geneticists); Skin, hair, and nail specialists (dermatologists)
- Expert care
- Expert lists: Foundation for Ichthyosis and Related Skin Types
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Foundation for Ichthyosis and Related Skin Types and other patient organizations
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD says changes in genes (also called variants) cause this condition. It is autosomal dominant, meaning one changed copy of the gene is enough.
Also known as: keratosis palmaris et plantaris with clinodactyly; palmoplantar keratoderma-clinodactyly syndrome
Patient organizations
- Foundation for Ichthyosis and Related Skin TypesKeratosis palmaris et plantaris-clinodactyly syndrome · United States
- Children's Skin Disease FoundationSkin diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Keratosis palmaris et plantaris-clinodactyly syndrome.
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