Living with Hyperbiliverdinemia
A rare condition in which skin, urine, and body fluids look green because of a pigment called biliverdin.
Understanding Hyperbiliverdinemia
The green color is due to high blood levels of a pigment called biliverdin. It occurs with a blocked flow of bile or with liver failure. It has also been linked to malnutrition, medicines, and a birth condition called congenital biliary atresia. It often shows in adults.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Green urine
- Green color of skin and eye whites
- Reduced liver function
- Gallstones
- Slowed or blocked bile flow (cholestasis)
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include digestive system specialists and genetic specialists.
- 3Consider genetic testing
Changes in BLVRA are linked to this condition. Genetic testing and counseling can help confirm a diagnosis and explain what it means for your family.
Care & treatment
- Care team
- Digestive system specialists (gastroenterologists); Genetic specialists (geneticists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with rare disease patient organizations for support
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
Changes in the BLVRA gene cause this condition. GARD lists autosomal dominant and autosomal recessive inheritance.
Also known as: green jaundice; hblvd
Patient organizations
Rare-disease groups that can help
- Global GenesRare Diseases · United States
- National Organization for Rare DisordersRare Diseases · United States
- Genetic AllianceRare Diseases · United States
- RARE FoundationRare Diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Hyperbiliverdinemia.
Explore research for Hyperbiliverdinemia
Explore actively recruiting Hyperbiliverdinemia studies with HealthSpark.
Find actively recruiting studies for Hyperbiliverdinemia with HealthSpark. Share your city to explore research near you.
- Recruiting studies from ClinicalTrials.gov
- Share your city to look for research near you
- Eligibility is confirmed by the study team
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Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.
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