Living with Hereditary painful callosities
A rare inherited skin condition with thick, painful patches on the pressure points of the feet and sometimes the hands.
Understanding Hereditary painful callosities
The patches are round and thickened, without redness. Sometimes the knees and shins are also affected, and the skin around or under the nails may thicken. Blisters can form at the edge of the calluses.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Pain
- Thick patches on the palms and soles
- Calluses on pressure points of the feet
- Calluses on the hands
- Blisters at the edge of calluses
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include genetic specialists and skin, hair, and nail specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
- 4Connect with expert centers
Foundation for Ichthyosis and Related Skin Types may keep lists of experts for this condition.
Care & treatment
- Care team
- Genetic specialists (geneticists); Skin, hair, and nail specialists (dermatologists)
- Expert care
- Expert lists: Foundation for Ichthyosis and Related Skin Types
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Foundation for Ichthyosis and Related Skin Types and other patient organizations
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD says changes in genes (also called variants) cause this condition. It is autosomal dominant, so one changed copy of the gene is enough.
Also known as: callosities, painful plantar; keratosis palmoplantaris nummularis; plamoplantar hyperkeratosis nummularis; plamoplantar keratoderma nummularis; ppk nummularis
Patient organizations
- Foundation for Ichthyosis and Related Skin TypesHereditary painful callosities · United States
- Children's Skin Disease FoundationSkin diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Hereditary painful callosities.
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