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Living with Goblet cell carcinoma

A rare tumor, usually in the appendix, with features of two tumor types.

Understanding Goblet cell carcinoma

Goblet cell carcinoma (goblet cell carcinoid) is a rare tumor that normally occurs in the appendix.

It shows features of both a neuroendocrine tumor and a more aggressive cancer called adenocarcinoma. It is usually noticed in adulthood.

Signs & symptoms

Symptoms vary from person to person. GARD says people may develop:

  • Acute appendicitis
  • Belly pain
  • Diarrhea

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Specialists who may be involved include cancer specialists, digestive system specialists and hormone specialists.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

  4. Connect with expert centers

    Appendix Cancer/Pseudomyxoma Peritonei Research Foundation, Carcinoid Cancer Foundation and Neuroendocrine Tumor Research Foundation may keep lists of experts for this condition.

Care & treatment

Care team
Cancer specialists (oncologists); Digestive system specialists (gastroenterologists); Hormone specialists (endocrinologists)
Expert care
Expert lists: Appendix Cancer/Pseudomyxoma Peritonei Research Foundation, Carcinoid Cancer Foundation, Neuroendocrine Tumor Research Foundation
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with Appendix Cancer/Pseudomyxoma Peritonei Research Foundation and other patient organizations
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
What stage is my tumor, and which tests show that?
What treatment options are available for this tumor type?
Which specialists should be on my care team?

Quick facts

Symptoms usually startAdult

GARD doesn't describe a cause for this condition yet.

EndocrineGastrointestinal

Also known as: appendix adenocarcinoid tumor; appendix adenocarcinoid tumour; appendix goblet cell carcinoid; appendix goblet cell carcinoid tumor; appendix goblet cell carcinoid tumour; appendix mixed carcinoid-adenocarcinoma

Patient organizations

Source: NIH GARD · Goblet cell carcinomaGARD ID 10414 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Goblet cell carcinoma.

Explore the Goblet cell carcinoma blog

Explore research for Goblet cell carcinoma

Explore actively recruiting Goblet cell carcinoma studies with HealthSpark.

HealthSpark

Find actively recruiting studies for Goblet cell carcinoma with HealthSpark. Share your city to explore research near you.

  • Recruiting studies from ClinicalTrials.gov
  • Share your city to look for research near you
  • Eligibility is confirmed by the study team

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I can help you find recruiting Goblet cell carcinoma studies. Enter a ZIP code, address or city below and I'll look within 50 miles.

Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.

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