Living with Gastric mucosal hypertrophy
Also called Menetrier disease: overgrowth of the stomach lining that causes thick stomach folds, pain, nausea, and protein loss.
Understanding Gastric mucosal hypertrophy
Overgrowth of mucous cells in the stomach lining makes the stomach folds larger. This leads to extra mucus, protein loss from the stomach, and low or no stomach acid. It can start from childhood to adulthood.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Pain in the upper middle belly
- Nausea
- Vomiting
- Weight loss
- Swelling in the arms and legs (peripheral edema)
- Lack of energy and strength (asthenia)
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include digestive system specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
Care & treatment
- Care team
- Digestive system specialists (gastroenterologists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with American Cancer Society
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
The cause is largely not known. Some cases are linked to infection, especially in children, where cytomegalovirus (CMV) infection can be the cause.
Also known as: adenopapillomatosis gastrica; chronic hypertrophic gastritis; familial giant hypertrophic gastritis; gastric hyperplasia; gastric mucosal hyperplasia; gastritis hypertrophic gigantica
Patient organizations
- American Cancer SocietyGastric mucosal hypertrophy · United States
You are more than your diagnosis
Perspectives from people navigating life with Gastric mucosal hypertrophy.
Explore research for Gastric mucosal hypertrophy
Explore actively recruiting Gastric mucosal hypertrophy studies with HealthSpark.
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- Recruiting studies from ClinicalTrials.gov
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- Eligibility is confirmed by the study team
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Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.
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