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Living with Erythema palmare hereditarium

A harmless inherited skin condition with lasting redness on the palms of the hands, present from birth.

Understanding Erythema palmare hereditarium

Erythema palmare hereditarium is a rare, benign (not harmful) inherited skin condition with permanent redness of the palms.

It is present in newborns and infants. The redness has sharp edges and often appears on the fleshy parts of the palm and the fingers, sometimes with tiny spidery blood vessels. It does not cause pain, itching, or burning.

Signs & symptoms

GARD describes these features in its summary:

  • Lasting redness of the palms
  • Sharply edged red areas
  • Tiny widened blood vessels (telangiectasia)
  • No pain, itching, or burning

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Specialists who may be involved include genetic specialists and skin, hair, and nail specialists.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

Care & treatment

Care team
Genetic specialists (geneticists); Skin, hair, and nail specialists (dermatologists)
Expert care
Ask about multidisciplinary care centers for rare conditions
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with Children's Skin Disease Foundation
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
Does this need any treatment?
Could this pass to my children?
Is any other follow-up needed?

Quick facts

Symptoms usually startNewborn and as an Infant
InheritanceAutosomal Dominant

Changes in genes cause this condition. It is autosomal dominant, which means a change in one copy of the gene can cause it. GARD does not name the gene.

GeneticSkin

Also known as: lane disease; red palms disease

Patient organizations

Broader rare-disease groups

Source: NIH GARD · Erythema palmare hereditariumGARD ID 17157 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Erythema palmare hereditarium.

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