Living with Distal monosomy 10p
A chromosome condition with a missing piece of chromosome 10 that can affect growth, learning, hearing, and facial features.
Understanding Distal monosomy 10p
How it affects a person depends on the size and location of the missing piece. Features can include low birth weight, slow growth, developmental delay, low muscle tone, and trouble communicating. Birth defects, other medical problems, and distinctive facial features may also be present. Most of these deletions are not inherited and happen by chance, but some come from a parent's chromosome rearrangement.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Severe delays in overall development
- Intellectual disability
- Small head size (microcephaly)
- Hearing loss
- Short height
- Heart or blood vessel differences
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include genetic specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
Care & treatment
- Care team
- Genetic specialists (geneticists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Chromosome Disorder Outreach
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
A piece of chromosome 10 is missing. Most 10p deletions are not inherited and happen by chance, but some occur because a parent has a rearrangement of chromosomes, and a parent may have the same deletion.
Also known as: digeorge syndrome 2; digeorge syndrome/velocardiofacial syndrome complex 2; distal 10p deletion; distal monosomy type 10p; monosomy 10pter; telomeric deletion 10p
Patient organizations
- Chromosome Disorder OutreachChromosome disorders · United States
Broader rare-disease groups
- Global GenesRare Diseases · United States
- National Organization for Rare DisordersRare Diseases · United States
- Genetic AllianceRare Diseases · United States
- RARE FoundationRare Diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Distal monosomy 10p.
Explore research for Distal monosomy 10p
Explore actively recruiting Distal monosomy 10p studies with HealthSpark.
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- Recruiting studies from ClinicalTrials.gov
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- Eligibility is confirmed by the study team
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Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.
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