Living with Dentinogenesis imperfecta type 2
A rare, severe form of dentinogenesis imperfecta in which teeth are weak and discolored.
Understanding Dentinogenesis imperfecta type 2
People may have weak, discolored teeth. Both baby and permanent teeth are affected, and people with this type have no normal teeth. Hearing loss from inner ear changes has been found in some people. GARD lists onset in childhood.
Signs & symptoms
GARD doesn't list a symptom list. Based on its summary, features include:
- Weak teeth
- Discolored teeth
- Hearing loss from inner ear changes (in some people)
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include genetic specialists and gum, teeth and mouth specialists.
- 3Consider genetic testing
Changes in DSPP are linked to this condition. Genetic testing and counseling can help confirm a diagnosis and explain what it means for your family.
Care & treatment
- Care team
- Genetic specialists (geneticists); Gum, teeth and mouth specialists (odontologists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with rare disease patient organizations for support
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
Changes in the DSPP gene cause this condition. It is autosomal dominant, so a changed copy of the gene from one parent can be enough.
Also known as: capdepont teeth; dentinogenesis imperfecta - shield's type ii; dentinogenesis imperfecta 1; dentinogenesis imperfecta type 1; dentinogenesis imperfecta, shields type 2; dentinogenesis imperfecta, shields type ii
Patient organizations
Rare-disease groups that can help
- Global GenesRare Diseases · United States
- National Organization for Rare DisordersRare Diseases · United States
- Genetic AllianceRare Diseases · United States
- RARE FoundationRare Diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Dentinogenesis imperfecta type 2.
Explore research for Dentinogenesis imperfecta type 2
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- Recruiting studies from ClinicalTrials.gov
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- Eligibility is confirmed by the study team
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Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.
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