Living with Cogan-Reese syndrome
An eye condition affecting one eye, usually in young to middle-aged women, with changes to the iris and a risk of glaucoma.
Understanding Cogan-Reese syndrome
ICE syndromes mostly affect young to middle-aged women, and some cases have been reported in children. Features can include a matted or smudged look to the iris surface, small colored lumps on the iris, parts of the iris attaching to the cornea, and increased eye pressure (glaucoma).
Signs & symptoms
Symptoms vary from person to person. GARD says they may include:
- Matted or smudged look of the iris
- Small colored lumps on the iris
- Parts of the iris stuck to the cornea
- Increased eye pressure (glaucoma)
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include eye disease specialists and genetic specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
Care & treatment
- Care team
- Eye disease specialists (ophthalmologists); Genetic specialists (geneticists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with rare disease patient organizations for support
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD doesn't describe a cause for this condition yet.
Also known as: iris nevus syndrome; nodular unilateral glaucoma
Patient organizations
Rare-disease groups that can help
- Global GenesRare Diseases · United States
- National Organization for Rare DisordersRare Diseases · United States
- Genetic AllianceRare Diseases · United States
- RARE FoundationRare Diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Cogan-Reese syndrome.
Explore research for Cogan-Reese syndrome
Explore actively recruiting Cogan-Reese syndrome studies with HealthSpark.
Find actively recruiting studies for Cogan-Reese syndrome with HealthSpark. Share your city to explore research near you.
- Recruiting studies from ClinicalTrials.gov
- Share your city to look for research near you
- Eligibility is confirmed by the study team
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Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.
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