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Living with Choriocarcinoma

A fast-spreading type of tumor that starts from tissue connected with pregnancy and makes large amounts of a hormone called hCG.

Understanding Choriocarcinoma

Choriocarcinoma is a malignant (cancerous) form of trophoblastic tumor that can spread to other parts of the body.

Unlike a hydatidiform mole, it has no chorionic villi. It is made of sheets of undifferentiated trophoblast cells and produces large amounts of chorionic gonadotropin (hCG). DNA tests can show whether it came from the placenta (fetal origin) or not.

Signs & symptoms

GARD doesn't list specific symptoms for this condition yet.

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Your doctor may refer you to a specialist who knows rare conditions.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

Care & treatment

Care team
A doctor familiar with rare conditions, plus specialists as needed
Expert care
Ask about multidisciplinary care centers for rare conditions
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with American Cancer Society and other patient organizations
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
What do my hCG levels show, and how will we track them?
Has the cancer spread, and what tests will show that?
Which specialists should be on my care team?

Quick facts

GARD doesn't describe a cause for this condition yet. DNA tests can show whether the tissue came from the placenta or from another source.

Also known as: chorioblastoma; choriocarcinoma (disease); choriocarcinoma, malignant; chorioepithelioma; chorion carcinoma; chorionepithelioma

Patient organizations

Source: NIH GARD · ChoriocarcinomaGARD ID 6059 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Choriocarcinoma.

Explore the Choriocarcinoma blog

Explore research for Choriocarcinoma

Explore actively recruiting Choriocarcinoma studies with HealthSpark.

HealthSpark

Find actively recruiting studies for Choriocarcinoma with HealthSpark. Share your city to explore research near you.

  • Recruiting studies from ClinicalTrials.gov
  • Share your city to look for research near you
  • Eligibility is confirmed by the study team

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I can help you find recruiting Choriocarcinoma studies. Enter a ZIP code, address or city below and I'll look within 50 miles.

Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.

Get Signals for Choriocarcinoma

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HealthStoryfor Choriocarcinoma

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HealthStory evolves private journaling with a living AI journal that talks back and asks thoughtful questions, helping you capture your Choriocarcinoma experiences more deeply and prepare for better conversations with your doctors and care team.

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