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Living with Cholera

An infection of the small intestine caused by bacteria in contaminated food or water, which can cause watery diarrhea and dehydration.

Understanding Cholera

Cholera is an infection of the small intestines caused by the bacterium Vibrio cholerae.

It can range from mild to severe, and many people have no obvious signs. A small share of people have severe watery diarrhea and vomiting, leading to rapid fluid loss, dehydration, and shock. People get cholera from food or water contaminated with the bacteria. It occurs most often in places without water treatment, good sanitation, and hygiene.

Signs & symptoms

Symptoms vary from person to person. GARD lists these among the most common:

  • Diarrhea
  • Vomiting
  • Dehydration
  • Less urine than usual
  • Fast heart rate and low blood pressure
  • Muscle spasms and weakness

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Your doctor may refer you to a specialist who knows rare conditions.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

Care & treatment

Care team
A doctor familiar with rare conditions, plus specialists as needed
Expert care
Ask about multidisciplinary care centers for rare conditions
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with rare disease patient organizations for support
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
What are the signs of dehydration that need urgent care?
How can we make drinking water and food safe at home?
Should others in my household be checked or protected?

Quick facts

Symptoms usually startany time in life

Cholera is caused by the bacterium Vibrio cholerae. People get it by eating or drinking food or water that has the bacteria in it.

Infectious

Also known as: cholera - vibrio cholerae; cholera due to vibrio cholerae; vibrio cholerae; vibrio cholerae caused disease or disorder; vibrio cholerae disease or disorder; vibrio cholerae infection

Patient organizations

Rare-disease groups that can help

Source: NIH GARD · CholeraGARD ID 6043 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Cholera.

Explore the Cholera blog

Explore research for Cholera

Explore actively recruiting Cholera studies with HealthSpark.

HealthSpark

Find actively recruiting studies for Cholera with HealthSpark. Share your city to explore research near you.

  • Recruiting studies from ClinicalTrials.gov
  • Share your city to look for research near you
  • Eligibility is confirmed by the study team

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I can help you find recruiting Cholera studies. Enter a ZIP code, address or city below and I'll look within 50 miles.

Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.

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HealthStoryfor Cholera

Create a living journal that talks back

HealthStory evolves private journaling with a living AI journal that talks back and asks thoughtful questions, helping you capture your Cholera experiences more deeply and prepare for better conversations with your doctors and care team.

Start your Cholera journal

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