Living with Avellino corneal dystrophy
An inherited eye condition in which deposits build up in the cornea, the clear front of the eye.
Understanding Avellino corneal dystrophy
It causes small breadcrumb-like deposits and cracked-glass-like lines on the cornea. These can grow larger and spread through the whole middle layer. Some older people have blurry vision from cloudy cornea. Onset is listed as childhood.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Cloudy area in the center of the cornea
- Breadcrumb-like corneal deposits
- Reduced clarity of vision
- Cloudiness in the middle layer of the cornea
- Cracked-glass-like lines (lattice)
- Blurred vision (less common)
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include eye disease specialists and genetic specialists.
- 3Consider genetic testing
Changes in TGFBI are linked to this condition. Genetic testing and counseling can help confirm a diagnosis and explain what it means for your family.
Care & treatment
- Care team
- Eye disease specialists (ophthalmologists); Genetic specialists (geneticists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Corneal Dystrophy Foundation
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
It is caused by changes in the TGFBI gene. It is autosomal dominant, so a change in one copy of the gene can cause it.
Also known as: cda; cgd2; combined granular-lattice corneal dystrophies; combined granular-lattice corneal dystrophy; gcd2; gcdii
Patient organizations
- Corneal Dystrophy FoundationAvellino corneal dystrophy · United States
You are more than your diagnosis
Perspectives from people navigating life with Avellino corneal dystrophy.
Explore research for Avellino corneal dystrophy
Explore actively recruiting Avellino corneal dystrophy studies with HealthSpark.
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- Recruiting studies from ClinicalTrials.gov
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- Eligibility is confirmed by the study team
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Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.
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