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Living with Autoimmune hemolytic anemia, warm type

The most common form of autoimmune hemolytic anemia, in which antibodies destroy red blood cells at normal body temperature.

Understanding Autoimmune hemolytic anemia, warm type

Autoimmune hemolytic anemia, warm type is the most common form of autoimmune hemolytic anemia, in which antibodies attack and destroy red blood cells at or above normal body temperature.

The destruction (hemolysis) mainly happens in the spleen, so a mildly enlarged spleen is common. Symptoms are related to anemia. In severe disease, fever, chest pain, fainting, or heart failure may occur. It can occur at any time in life.

Signs & symptoms

Symptoms vary from person to person. GARD lists these among the most common:

  • Tiredness (fatigue)
  • Shortness of breath with activity
  • Pale skin
  • Palpitations
  • Headache and joint pain
  • Enlarged spleen

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Specialists who may be involved include blood and bone marrow specialists.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

  4. Connect with expert centers

    Autoimmune Association may keep lists of experts for this condition.

Care & treatment

Care team
Blood and bone marrow specialists (hematologists)
Expert care
Expert lists: Autoimmune Association
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with Autoimmune Association and other patient organizations
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
Is my anemia linked to another condition, like a lymphoproliferative disorder?
Which treatments reduce the immune attack?
Which symptoms mean I need urgent care?

Quick facts

Symptoms usually startany time in life

GARD says autoantibodies attach to and destroy red blood cells at temperatures equal to or above normal body temperature.

Blood

Also known as: aiha - warm autoimmune hemolytic anemia; hemolytic anemia due to warm antibody; waha; waiha; warm aiha; warm antibody hemolytic anemia

Patient organizations

Source: NIH GARD · Autoimmune hemolytic anemia, warm typeGARD ID 7876 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Autoimmune hemolytic anemia, warm type.

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