Living with Anti-glomerular basement membrane disease
An autoimmune disease in which the body attacks the lungs and kidneys.
Understanding Anti-glomerular basement membrane disease
Antibodies attack collagen in the kidney filters (glomeruli) and the lung air sacs. This causes kidney inflammation (glomerulonephritis) and bleeding in the lungs. It was once called Goodpasture syndrome or Goodpasture disease. It can begin at a variety of ages.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Blood in the urine (hematuria)
- Coughing up blood (hemoptysis)
- Cough and chest pain
- Trouble breathing
- Low red blood cells (anemia)
- Inflamed blood vessels (vasculitis)
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include autoimmune and inflammatory disease specialists, kidney specialists and lung and breathing specialists.
- 3Ask which tests can help
Your care team will decide which exams and tests can confirm the diagnosis.
- 4Connect with expert centers
Autoimmune Association and Vasculitis Foundation may keep lists of experts for this condition.
Care & treatment
- Care team
- autoimmune and inflammatory disease specialists (rheumatologists); Kidney specialists (nephrologists); Lung and breathing specialists (pulmonologists)
- Expert care
- Expert lists: Autoimmune Association, Vasculitis Foundation
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Autoimmune Association and other patient organizations
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD says it is thought to result from something in the environment, like smoking, infections, or certain drugs, in a person with genetic susceptibility, such as a specific HLA type.
Also known as: anti gbm - antiglomerular basement membrane disease; anti-gbm nephritis with pulmonary hemorrhage; anti-gbm syndrome; anti-glomerular basement membrane antibody disease; glomerulonephritis - pulmonary hemorrhage; goodpasture disease
Patient organizations
- Autoimmune AssociationAnti-glomerular basement membrane disease · United States
- Vasculitis FoundationAnti-glomerular basement membrane disease · United States
- National Kidney FoundationKidney diseases · United States
- Renal Support NetworkKidney diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Anti-glomerular basement membrane disease.
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