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Living with Amoebiasis due to Entamoeba histolytica

A parasitic infection caused by swallowing cysts of Entamoeba histolytica, mainly in tropical regions, ranging from no symptoms to bowel or liver illness.

Understanding Amoebiasis due to Entamoeba histolytica

Amoebiasis due to Entamoeba histolytica is a parasitic disease caused by a single-celled organism (protozoan) called Entamoeba histolytica.

It mainly occurs in tropical regions after a person swallows an amoebic cyst. Some people have no symptoms. Others develop amoebic colitis in the bowel or liver abscesses. Spread to other parts of the body is extremely rare. It can occur at any time in life.

Signs & symptoms

Symptoms vary from person to person. GARD's summary says they may include:

  • Severe belly pain
  • Blood and mucus in the stool
  • Fever and chills (with a liver abscess)
  • Weight loss
  • Enlarged liver
  • No symptoms in some people

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Your doctor may refer you to a specialist who knows rare conditions.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

Care & treatment

Care team
A doctor familiar with rare conditions, plus specialists as needed
Expert care
Ask about multidisciplinary care centers for rare conditions
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with rare disease patient organizations for support
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
Which tests confirm this infection?
How can I avoid catching it again?
Should my household members be tested?

Quick facts

Symptoms usually startany time in life

GARD says it is caused by the parasite Entamoeba histolytica, usually after swallowing an amoebic cyst.

Infectious

Patient organizations

Rare-disease groups that can help

Source: NIH GARD · Amoebiasis due to Entamoeba histolyticaGARD ID 18675 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Amoebiasis due to Entamoeba histolytica.

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