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Living with Acute lymphoid leukemia

A cancer in which the bone marrow makes too many lymphocytes, a type of white blood cell, in children or adults.

Understanding Acute lymphoid leukemia

Acute lymphoblastic leukemia (ALL) is a type of cancer in which the bone marrow makes too many lymphocytes, a type of white blood cell.

It may develop in children or adults. ALL spreads to the blood and may then spread to other areas, such as the lymph nodes, liver, spleen, central nervous system, and testicles. It can start at any time in life.

Signs & symptoms

Symptoms vary from person to person. GARD's summary says they may include:

  • Fever
  • Easy bruising or bleeding
  • Feeling tired
  • Loss of appetite
  • Pain in the bones or abdomen
  • Painless lumps in the neck, underarm, stomach, or groin

Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.

Diagnosis

  1. Talk with your doctor

    Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.

  2. See a specialist

    Specialists who may be involved include blood and bone marrow specialists and cancer specialists.

  3. Ask which tests can help

    Your care team will decide which exams and tests can confirm the diagnosis.

Care & treatment

Care team
Blood and bone marrow specialists (hematologists); Cancer specialists (oncologists)
Expert care
Ask about multidisciplinary care centers for rare conditions
Treatment
GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
Research
Clinical trials and observational studies may be options. See the research section below.

General information, not medical advice. Your care team makes the decisions.

Everyday life

Living with a rare condition is easier with support.

  • Connect with American Cancer Society and other patient organizations
  • Keep notes on symptoms, changes and questions for appointments
  • Ask about patient registries that help research
  • Look into financial aid and travel resources for care visits
Bring these questions to your next doctor visit
Which tests will show whether the leukemia has spread?
Do any risk factors apply to me or my child?
Which specialists should be on the care team?

Quick facts

Symptoms usually startany time in life

GARD says ALL is typically caused by random, non-inherited changes in the DNA of immature lymphocytes (lymphoblasts). Some people inherit a genetic susceptibility, and past cancer treatment or certain genetic conditions may raise the risk.

Blood

Also known as: acute lymphatic leukaemia; acute lymphatic leukemia; acute lymphoblastic leukaemia; acute lymphoblastic leukaemia (all); acute lymphoblastic leukaemia (disease); acute lymphoblastic leukemia

Patient organizations

Source: NIH GARD · Acute lymphoid leukemiaGARD ID 522 · GARD page updated September 2026 · Plain-language summary by Know Rare; editorial review pending. General information, not medical advice.

You are more than your diagnosis

Perspectives from people navigating life with Acute lymphoid leukemia.

Explore the Acute lymphoid leukemia blog

Explore research for Acute lymphoid leukemia

Explore actively recruiting Acute lymphoid leukemia studies with HealthSpark.

HealthSpark

Find actively recruiting studies for Acute lymphoid leukemia with HealthSpark. Share your city to explore research near you.

  • Recruiting studies from ClinicalTrials.gov
  • Share your city to look for research near you
  • Eligibility is confirmed by the study team

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Powered by HealthSpark, our AI chat helper · Study information from ClinicalTrials.gov · Eligibility is confirmed by the study team.

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