Living with Acute febrile neutrophilic dermatosis
A skin condition (Sweet syndrome) with fever, joint pain, and painful skin bumps mainly on the face, neck, back, and arms.
Understanding Acute febrile neutrophilic dermatosis
The skin lesions appear mainly on the face, neck, back, and arms. Middle-aged women are most likely to develop it, but it can also affect men, older adults, and infants. GARD lists the onset as adulthood.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Fever that comes and goes
- Painful red skin bumps and patches
- Skin nodules
- Joint pain (arthralgia)
- Muscle aches (myalgia)
- High white blood cell count
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include autoimmune and inflammatory disease specialists, genetic specialists and skin, hair, and nail specialists.
- 3Consider genetic testing
Changes in MEFV are linked to this condition. Genetic testing and counseling can help confirm a diagnosis and explain what it means for your family.
Care & treatment
- Care team
- autoimmune and inflammatory disease specialists (rheumatologists); Genetic specialists (geneticists); Skin, hair, and nail specialists (dermatologists)
- Expert care
- Ask about multidisciplinary care centers for rare conditions
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Children's Skin Disease Foundation
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
GARD says the exact cause often isn't known. It may be a reaction to things like sun, infections, or some medicines, and it can occur with some cancers. GARD lists the MEFV gene.
Also known as: afnd; febrile neutrophilic dermatosis; gomm button disease; sweet disease; sweet syndrome
Patient organizations
- Children's Skin Disease FoundationSkin diseases · United States
Broader rare-disease groups
- Global GenesRare Diseases · United States
- National Organization for Rare DisordersRare Diseases · United States
- Genetic AllianceRare Diseases · United States
- RARE FoundationRare Diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Acute febrile neutrophilic dermatosis.
Explore research for Acute febrile neutrophilic dermatosis
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