Living with Acrokerato-elastoidosis
A rare skin condition with small, yellowish, thickened bumps on the palms of the hands and soles of the feet.
Understanding Acrokerato-elastoidosis
The bumps are small, round to oval, and yellowish. They are most often on the palms and soles, and in severe cases can spread to the backs of the hands and feet. It can occur on its own or run in families. GARD lists onset as teenager and adult.
Signs & symptoms
Symptoms vary from person to person. GARD lists these among the most common:
- Yellowish thickened bumps (papules)
- Thickened skin on palms and soles
- Thick upper layer of skin
- Fragmented elastic fibers in the skin
- Hard, thick skin patches
Not everyone has every symptom. GARD's list comes from the Human Phenotype Ontology.
Diagnosis
- 1Talk with your doctor
Share the symptoms you've noticed, when they started and your family health history. Notes and photos can help.
- 2See a specialist
Specialists who may be involved include genetic specialists and skin, hair, and nail specialists.
- 3Consider genetic testing
Changes in CCDC91 are linked to this condition. Genetic testing and counseling can help confirm a diagnosis and explain what it means for your family.
- 4Connect with expert centers
Foundation for Ichthyosis and Related Skin Types may keep lists of experts for this condition.
Care & treatment
- Care team
- Genetic specialists (geneticists); Skin, hair, and nail specialists (dermatologists)
- Expert care
- Expert lists: Foundation for Ichthyosis and Related Skin Types
- Treatment
- GARD doesn't list specific treatments for this condition. Your care team will tailor care to your symptoms.
- Research
- Clinical trials and observational studies may be options. See the research section below.
General information, not medical advice. Your care team makes the decisions.
Everyday life
Living with a rare condition is easier with support.
- Connect with Foundation for Ichthyosis and Related Skin Types and other patient organizations
- Keep notes on symptoms, changes and questions for appointments
- Ask about patient registries that help research
- Look into financial aid and travel resources for care visits
Quick facts
Changes in the CCDC91 gene cause this condition. It is listed as autosomal dominant, and it can also occur without a family history.
Also known as: acrokeratoelastoidosis of costa; ake; collagenous plaques of hands and feet; keratoderma, palmoplantar, punctate type 3; palmoplantar keratoderma, punctate type iii; ppkp3
Patient organizations
- Foundation for Ichthyosis and Related Skin TypesAcrokerato-elastoidosis · United States
- Children's Skin Disease FoundationSkin diseases · United States
You are more than your diagnosis
Perspectives from people navigating life with Acrokerato-elastoidosis.
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